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Hantavirus Alert: Two Singapore Residents Tested After Cruise Ship Andes Cluster

The MV Hondius cruise ship reported an outbreak of Andes hantavirus, with eight cases linked to the cluster on the ship so far. PHOTO: REUTERS
The MV Hondius cruise ship reported an outbreak of Andes hantavirus, with eight cases linked to the cluster on the ship so far. PHOTO: REUTERS
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Pair isolated at NCID after sharing flight with confirmed MV Hondius case; risk to public deemed low.

Two Singapore residents who travelled on the MV Hondius cruise ship linked to an Andes hantavirus cluster are being tested and quarantined, as authorities move to contain any possible spread from the rare rodent-borne virus.

Two Travellers Isolated And Tested At NCID
The Communicable Diseases Agency (CDA) said on May 7 that it was notified on May 4 and 5 of two Singapore residents who had been aboard the MV Hondius, a cruise ship reporting an Andes hantavirus outbreak. Both are now isolated at the National Centre for Infectious Diseases (NCID) and are being tested. One, a 67-year-old Singaporean man who arrived on May 2, has a runny nose but is otherwise well; the other, a 65-year-old Singapore permanent resident who arrived on May 6, has no symptoms. Test results are pending.

Exposure Linked To Flight From St Helena
Both individuals had boarded the MV Hondius when it departed Ushuaia, Argentina, on April 1. After disembarking, they shared a flight from St Helena Island to Johannesburg, South Africa, on April 25 with a passenger later confirmed to have Andes hantavirus. That passenger did not travel to Singapore and subsequently died in South Africa, CDA said. St Helena is a remote South Atlantic island about 2,000km off the African coast, complicating contact tracing and follow-up.

Quarantine, Monitoring And Contact Tracing Protocols
If the two residents test negative, they will still undergo a 30-day quarantine from their last exposure date, as most hantavirus infections are expected to become apparent within that window. They will be tested again before release and then monitored remotely for the rest of a 45-day incubation period, for example by reporting their health status daily through tracking apps. If either test is positive, the patient will remain hospitalised for monitoring and supportive treatment, and CDA will initiate contact tracing to identify anyone exposed during the infectious period; close contacts will also be quarantined.

MV Hondius Cluster And Global Risk Assessment
So far, eight hantavirus cases, including three deaths, have been linked to the MV Hondius cluster. The World Health Organization (WHO) said at a May 7 briefing that five of eight suspected cases tied to the vessel have been confirmed and assessed the overall risk to the global population as low. While hantaviruses usually spread from rodents to humans rather than person to person, the Andes virus, found in parts of South America, has been associated with limited human-to-human transmission, making close follow-up of exposed passengers prudent.

How Hantavirus Spreads And How To Reduce Risk
Duke-NUS Medical School’s Professor Ooi Eng Eong said hantaviruses are naturally carried by rodents, including brown and black rats found in cities such as Singapore. Infection can occur via contaminated food, inhalation of dust tainted with rodent urine, droppings or saliva, and through bites or scratches; human-to-human spread is rare and mainly linked to Andes virus. Symptoms typically include fever, body aches, fatigue, gastrointestinal upset and difficulty breathing, and can progress rapidly to hantavirus pulmonary syndrome, shock and death. There is no specific antiviral treatment or vaccine; care is supportive. CDA and WHO advise travellers to avoid contact with rodents and their excreta, keep accommodation clean and rodent-proof, use damp cleaning methods to reduce dust, maintain good hygiene, and seek prompt medical help if they become unwell, informing doctors of recent travel and possible rodent or patient exposure.

Singapore’s swift isolation and testing of two MV Hondius passengers, combined with extended quarantine and monitoring, reflects a cautious approach to a rare but potentially severe virus whose main risk lies in rodent exposure rather than sustained human transmission. For Indonesians and Singaporeans, the case underscores the importance of travel history in diagnosing emerging infections and of basic rodent-control and hygiene measures when camping, hiking or visiting rural areas where hantaviruses may circulate.

Sources: Straits Times (2026) , CNA (2026)

Keywords: Andes Hantavirus Cluster, Singapore Residents Tested, Cruise Ship Outbreak, St Helena Flight Exposure, WHO Risk Assessment, Rodent Borne Infection

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